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Article

Interpreting sulfhemoglobin and methemoglobin in patients with cyanosis: An overview of patients with M-hemoglobin variants.

International journal of laboratory hematology - 1 Aug 2021

Rangan Aruna, Savedra Michelle E, Dergam-Larson Camila, Swanson Kenneth C, Szuberski Jessica, Go Ronald S, Porter Tavanna R, Brunker Sarah E, Shi Min, Nguyen Phuong L, Hoyer James D, Oliveira Jennifer L

Abstract excerpt

INTRODUCTION: Methemoglobin (MetHb) and sulfhemoglobin (SHb) measurements are useful in the evaluation of cyanosis. When one or both values are elevated, additional analysis is important to establish the etiology of the disorder. Methemoglobinemia occurs from acquired or hereditary causes with diverse treatment considerations, while true sulfhemoglobinemia is only acquired and treatment is restricted to toxin...

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PMID: 34092029
DOI: 10.1111/ijlh.13581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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