Article
Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers.
Environmental and molecular mutagenesis - 1 Jan 2002
Salama Salama A, Au William W, Hunter Glenn C, Sheahan Richard G, Badary Osama A, Abdel-Naim Ashraf B, Hamada Farid M A
Abstract excerpt
Atherosclerosis (AR) is the leading cause of morbidity and mortality in the US and cigarette smoking is a major contributing factor to the disease. Like cigarette smoking in lung cancer, genetic susceptibility may be an important factor in determining who is more likely to develop AR. However, the current emphasis has been on susceptibility based on altered cardiovascular homeostasis. In this investigation, we...
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