Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alleles of a functional serotonin transporter promoter polymorphism are associated with major depression in alcoholics.

Alcoholism, clinical and experimental research - 1 Sept 2003

Nellissery Maggie, Feinn Richard S, Covault Jonathan, Gelernter Joel, Anton Raymond F, Pettinati Helen, Moak Darlene, Mueller Timothy, Kranzler Henry R

Abstract excerpt

BACKGROUND: Serotonergic neurotransmission has been implicated in the pathogenesis of both alcohol dependence and mood disorders and may therefore be important in understanding the pathophysiology of comorbid alcohol dependence and major depression. Studies of the association of these disorders with a functional polymorphism in the promoter region of the gene encoding the serotonin transporter protein (locus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black People

Share to Comorbidity

Share to Depressive Disorder, Major

Share to Membrane Glycoproteins

Share to Membrane Transport Proteins

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 14506400
DOI: 10.1097/01.ALC.0000085588.11073.BB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alleles of a functional serotonin transporter promoter polymorphism are associated with major depression in alcoholics.PMID 14506400Read ↗

Association study of alcoholism subtypes with a functional promoter polymorphism in the serotonin transporter protein gene.Semantic proximity Read ↗

Serotonin transporter gene polymorphisms, alcoholism, and suicidal behavior.Semantic proximity Read ↗

Serotonin transporter promoter polymorphism and monoamine oxidase type A VNTR allelic variants together influence alcohol binge drinking risk in young women.Semantic proximity Read ↗

The serotonin transporter gene and risk for alcohol dependence: a meta-analytic review.Semantic proximity Read ↗

Support for allelic association of a polymorphic site in the promoter region of the serotonin transporter gene with risk for alcohol dependence.Semantic proximity Read ↗

Influence of the serotonin transporter gene on comorbid disorders among alcohol-dependent individuals.Semantic proximity Read ↗

Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.Semantic proximity Read ↗

Serotonin transporter (5-HTTLPR) and monoamine oxidase (MAOA) promoter polymorphisms in women with severe alcoholism.Semantic proximity Read ↗

Variation in the Serotonin Transporter Gene and Alcoholism: Risk and Response to Pharmacotherapy.Semantic proximity Read ↗

Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence.Semantic proximity Read ↗

Clinical Implications of Genetic Variation in the Serotonin Transporter Promoter RegionSemantic proximity Read ↗

Alcohol Dependence and Genetic Variability in the Serotonin Pathway among Currently and Formerly Alcohol-Dependent Males.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.