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Article

Genetic changes in uroepithelial tumors of patients with Balkan endemic nephropathy.

Journal of nephrology - 1 Jan 2000

Toncheval Draga I, Atanassova Srebrena Y, Gergov Tzvetan D, Todorovska Elena G, Roeva Ivana G, Georgiev Tchavdar H, Fink-Gremmels Joanna, Zaharieva Boriana M

Abstract excerpt

BACKGROUND: Balkan endemic nephropathy (BEN) is seen in certain regions of the Balkan Peninsula. The patients are predisposed to epithelial cell tumors of the urinary tract. These tumors have not been genetically investigated so far. METHODS: We studied the loss of heterozygosity (LOH) in three BEN-associated tumors at seven microsatellite loci at 3q21.3 - 3q27.3. Comparative genomic hybridization (CGH) was also...

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PMID: 12243368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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