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Article

Induction of apoptosis and inhibition of cell growth by developmental regulator hTBX5.

Biochemical and biophysical research communications - 20 Sept 2002

He Ming-Liang, Chen Ying, Peng Ying, Jin Dadao, Du Dan, Wu Jun, Lu Ping, Lin Marie C, Kung Hsiang-Fu

Abstract excerpt

T box (Tbx) genes are a large family of transcription regulators that play critical roles in invertebrate and vertebrate development. Mutations in Tbx5 gene have been found to cause Holt-Oram syndrome (HOS) in humans. Partial dysfunction of TBX5 in mouse also causes HOS phenotype. Little is known about its molecular and cellular mechanism. Here, we report that ectopic expression of TBX5 inhibited colony...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12237100
DOI: 10.1016/s0006-291x(02)02142-3

Genes

TBX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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