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Article

Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms.

EMBO reports - 1 Oct 2002

Wee Hee-Jun, Huang Gang, Shigesada Katsuya, Ito Yoshiaki

Abstract excerpt

The RUNX family represents a small group of heterodimeric transcription factors that master-regulate osteogenesis and hematopoiesis in mammals. Their genetic defects cause human diseases such as cleidocranial dysplasia (CCD) and acute myelogenous leukemia. However, the mechanism(s) regulating their functions are still poorly understood. Here, we report a novel observation that suggests that the...

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Identifiers

PMID: 12231506
DOI: 10.1093/embo-reports/kvf193
PMCID: PMC1307622

Genes

RUNX2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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