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Longitudinal personality changes among presymptomatic Huntington disease gene carriers.

Neuropsychiatry, neuropsychology, and behavioral neurology - 1 Sept 2002

Kirkwood Sandra Close, Siemers Eric, Viken Richard, Hodes M E, Conneally P Michael, Christian Joe C, Foroud Tatiana

Abstract excerpt

OBJECTIVE: To determine whether longitudinal changes in personality as measured by the Minnesota Multiphasic Personality Inventory (MMPI) can be detected among clinically presymptomatic individuals carrying the expanded Huntington disease (HD) allele. BACKGROUND: Emotional symptoms are considered one of the cardinal features of HD. However, the literature is replete with conflicting reports of psychiatric...

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PMID: 12218712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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