Article
Irritability in a Prospective Cohort of Huntington's Disease Mutation Carriers.
The Journal of neuropsychiatry and clinical neurosciences - 1 Jan 2015
Bouwens Joseph A, van Duijn Erik, van der Mast Roos C, Roos Raymund A C, Giltay Erik J
Abstract excerpt
A key neuropsychiatric symptom of Huntington's disease, irritability, contributes to a decline in functioning and to great distress in both patients and their caregivers. To identify mutation carriers prone to the development of irritability, this study aimed to investigate the course and temporal relationships between irritability and other neuropsychiatric symptoms. A cohort of 90 mutation carriers was followed...
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