Article
Harmful drinking in military veterans with post-traumatic stress disorder: association with the D2 dopamine receptor A1 allele.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Young R McD, Lawford B R, Noble E P, Kann B, Wilkie A, Ritchie T, Arnold L, Shadforth S
Abstract excerpt
AIMS: The frequency of the Taq I A alleles (A1 and A2) of the D2 dopamine receptor (DRD2) gene was examined in Caucasian post-traumatic stress disorder (PTSD) patients and controls. RESULTS: In 91 PTSD patients, the frequency of the A1 allele was higher (P = 6.12 x 10(-3)) than in the 51 controls. In the 38 PTSD harmful drinkers (>or=60 g alcohol/day), A1 allelic frequency was higher (P = 3.91 x 10(-2)) than in...
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