Article
Type I gamma-GT mRNA is expressed in B16 melanoma and levels correlate with pigmentation.
Pigment cell research - 1 Oct 2002
Chaubal Vaishali A, Nair Sujit S, Mojamdar Manoj V
Abstract excerpt
Gamma-glutamyl transpeptidase (gamma-GT), an ectoenzyme involved mainly in glutathione metabolism, is expressed in B16 melanoma cells. B16 melanoma cells under continuous culture conditions show a phenotypic drift from melanotic to amelanotic and re-melanotic stages. We have investigated the regulation of gamma-GT in B16 melanoma cells under such different pigmentary conditions. High levels of gamma-GT messenger...
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