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Article

Association of the G289S single nucleotide polymorphism in the HSD17B3 gene with prostate cancer in Italian men.

The Prostate - 15 Sept 2002

Margiotti Katia, Kim Eugene, Pearce C Leigh, Spera Enrico, Novelli Giuseppe, Reichardt Juergen K V

Abstract excerpt

BACKGROUND: Prostate cancer is a significant public health problem in this country. Substantial data support a plausible role for androgens in the etiology of this disease. The human HSD17B3 gene encodes the testicular (or type III) 17 beta-hydroxysteroid dehydrogenase enzyme, which catalyzes testosterone biosynthesis in men. METHODS: We have investigated the G289S (glycine at codon 289 replaced by serine)...

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Identifiers

PMID: 12210481
DOI: 10.1002/pros.10134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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