Article
Acidophilic character of yeast PID261/BUD32, a putative ancestor of eukaryotic protein kinases.
Biochemical and biophysical research communications - 6 Sept 2002
Facchin Sonia, Sarno Stefania, Marin Oriano, Lopreiato Raffaele, Sartori Geppo, Pinna Lorenzo A
Abstract excerpt
Yeast piD261/Bud32 and its homologues are present in eukaryotes and in archaea but not in bacteria and are believed to make up a primordial branch of the eukaryotic protein kinase superfamily. Here, we show that, at variance with the majority of Ser/Thr protein kinases which recognize phosphoacceptor sites specified by basic and/or proline residues, piD261 phosphorylates in vitro a number of acidic proteins and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.