Article
Key amino acid residues required for aryl migration catalysed by the cytochrome P450 2-hydroxyisoflavanone synthase.
The Plant journal : for cell and molecular biology - 1 Sept 2002
Sawada Yuji, Kinoshita Kengo, Akashi Tomoyoshi, Aoki Toshio, Ayabe Shin-Ichi
Abstract excerpt
Isoflavonoids are distributed predominantly in leguminous plants, and play pivotal roles in the interaction of host plants with biological environments. Isoflavones in the diet also have beneficial effects on human health as phytoestrogens. The isoflavonoid skeleton is constructed by the CYP93C subfamily of cytochrome P450s in plant cells. The reaction consists of hydroxylation of the flavanone molecule at C-2...
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