Article
Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with obstetric cholestasis.
European journal of obstetrics, gynecology, and reproductive biology - 10 Sept 2002
Eloranta Marja-Lissa, Heiskanen Jaana T M, Hiltunen Mikko J, Mannermaa Arto J, Punnonen Kari R A, Heinonen Seppo T
Abstract excerpt
OBJECTIVE: To investigate the contribution of the estrogen receptor alpha (ERalpha) polymorphism in the development of obstetric cholestasis and to determine whether multidrug resistance 3 (MDR3) gene 1712delT mutation detected in French patients is also present in Finnish women with obstetric cholestasis. STUDY DESIGN: In a retrospective case-control study, two ERalpha polymorphisms and MDR3 gene mutation...
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