Article
[Study on the association between estrogen receptor alpha gene polymorphism and intrahepatic cholestasis of pregnancy].
Zhonghua fu chan ke za zhi - 1 May 2006
Zhang Li, Liu Shu-yun, Shi Qing-yun, Chen Qiang, Zou Hai, Xing Ai-yun
Abstract excerpt
OBJECTIVE: To investigate the relationship between estrogen receptor alpha (ERalpha) gene polymorphism and intrahepatic cholestasis of pregnancy (ICP). METHODS: The Xba I and Pvu II polymorphisms in intron 1 of ER alpha gene were detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 100 pregnant women with ICP (ICP group) and 100 normal pregnant women (control group)....
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