Article
A multistate model for the genetic analysis of the ageing process.
Statistics in medicine - 15 Sept 2002
Giard Nicole, Lichtenstein Paul, Yashin Anatoli I
Abstract excerpt
In this paper a multivariate frailty model is suggested that can be used in the genetic analysis of the ageing process as a whole, simplified to consisting of the states 'healthy', 'disabled' and 'deceased'. The model allows us to evaluate simultaneously the relative magnitude of genetic and environmental influences on frailty variables corresponding to the period of good health and to the life span. The frailty...
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