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Article

Frailty phenotypes in the elderly based on cluster analysis: a longitudinal study of two Danish cohorts. Evidence for a genetic influence on frailty.

Age (Dordrecht, Netherlands) - 1 Jun 2012

Dato Serena, Montesanto Alberto, Lagani Vincenzo, Jeune Bernard, Christensen Kaare, Passarino Giuseppe

Abstract excerpt

Frailty is a physiological state characterized by the deregulation of multiple physiologic systems of an aging organism determining the loss of homeostatic capacity, which exposes the elderly to disability, diseases, and finally death. An operative definition of frailty, useful for the classification of the individual quality of aging, is needed. On the other hand, the documented heterogeneity in the quality of...

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Identifiers

PMID: 21567248
DOI: 10.1007/s11357-011-9257-x
PMCID: PMC3337941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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