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Article

Multivariate frailty model with a major gene: application to genealogical data.

Studies in health technology and informatics - 1 Jan 2000

Begun A, Desjardins B, Iachine I, Yashin A

Abstract excerpt

Multivariate survival models are shown to be appropriate for the analysis of the genetic and the environmental nature of a human life-span. Models which involve continuously distributed individual frailty, play an important role in the genetic analysis of an individual's susceptibility to disease and death. These models, however, are not appropriate for the detection of the effects of separate genes on survival....

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PMID: 11187585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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