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Article

Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer.

Journal of cancer research and clinical oncology - 1 Aug 2002

Ward Robyn, Meldrum Cliff, Williams Rachael, Mokany Elisa, Scott Rodney, Turner Jenny, Hawkins Nicholas, Burgess Bronwyn, Groombridge Claire, Spigelman Allan

Abstract excerpt

PURPOSE: Identification of germline mutations in mismatch repair genes is increasingly being used to guide clinical practice in hereditary non-polyposis colon cancer. The aim of this study was to retrospectively assess the clinical utility of immunostaining and microsatellite instability testing...

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Share to Adaptor Proteins, Signal Transducing
Share to Base Pair Mismatch

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to Germ-Line Mutation

Share to Immunoenzyme Techniques

Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

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Source

Identifiers

PMID: 12200596
DOI: 10.1007/s00432-002-0361-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12200596-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer.PMID 12200596Read ↗

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