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Article

Properties of neurotoxic peptides related to the BRI gene.

Biochemical Society transactions - 1 Aug 2002

Austen B, el-Agnaf O, Nagala S, Patel B, Gunasekera N, Lee M, Lelyveld V

Abstract excerpt

Mutations in the BRI gene are thought to cause dementias in members of families. The clinical symptoms are similar to those of Alzheimer's disease, but with additional ocular and hearing deficits, and spasticity. The mutations lead to the release of the 34-residue peptides, ABri and ADan, in the...

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PMID: 12196136
DOI: 10.1042/bst0300557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12196136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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