Article
Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice.
Functional & integrative genomics - 1 Aug 2002
Masinde Godfred L, Li Xinmin, Gu Weikuan, Hamilton-Ulland Melanie, Mohan Subburaman, Baylink David J
Abstract excerpt
The genetic mechanisms that determine muscle size have not been elucidated, even though it is a key musculoskeletal parameter that reflects muscle strength. In this study, we performed a high-density genome-wide scan using 633 (MRL/MPJ x SJL/J) F(2) intercross 7-week-old mice to identify quantitative trait loci (QTL) involved in the determination of muscle size. Significant QTL were identified for muscle size and...
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