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Article

Propapoptotic effects of NF-kappaB in LNCaP prostate cancer cells lead to serine protease activation.

Cell death and differentiation - 1 Sept 2002

Kimura K, Gelmann E P

Abstract excerpt

LNCaP prostate cancer cells are resistant to induction of apoptosis by gamma-irradiation and partially sensitive to TNF-alpha or FAS antibody, irradiation sensitizes cells to apoptosis induced by FAS antibody or TNF-alpha. LNCaP cell clones stably expressing IkappaBalpha super repressor were resistant to apoptosis induced by death ligands in the presence or absence of irradiation. IkappaBalpha super repressor...

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Source

Identifiers

PMID: 12181748
DOI: 10.1038/sj.cdd.4401049

Genes

FAS
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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