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Article

Toll-like Receptor (TLR) Signaling in Response toAspergillus fumigatus

1 Oct 2002

Abstract excerpt

Aspergillus fumigatus causes life-threatening infections in patients with qualitative and quantitative defects in phagocytic function. Here, we examined the contribution of Toll-like receptor (TLR)-2, TLR4, the adapter protein MyD88, and CD14 to signaling in response to the three forms of A. fumigatus encountered during human disease: resting conidia (RC), swollen conidia (SC), and hyphae (H). Compared with...

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PMID: 12171914
DOI: 10.1074/jbc.m201683200

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