Article
Characterization of measles virus strains causing SSPE: a study of 11 cases.
Journal of neurovirology - 1 Aug 2002
Jin L, Beard S, Hunjan R, Brown D W G, Miller E
Abstract excerpt
Eleven subacute sclerosing panencephalitis (SSPE) cases diagnosed in the UK between 1965 and 2000 were investigated. The entire or partial matrix (M), hemagglutinin (H), and nucleoprotein (N) genes of measles virus (MV) were sequenced following direct RT-PCR amplification from brain tissues. All the M genes showed the characteristic biased hypermutations and a premature termination codon was detected in 5/11 M...
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