Article
Human and animal morbillivirus strains causing chronic neurological infections share key genotypic and phenotypic traits.
Proceedings of the National Academy of Sciences of the United States of America - 14 Jul 2026
Daniel Roji Melvin, Geiselhardt Franziska, Beythien Georg, Laudeley Kristin, Mirolo Monica, Jo Wendy K, Martino Laura, Beineke Andreas, Baumgärtner Wolfgang, Peters Martin, van den Brand Judith M A, Jensen Trine H, Kuiken Thijs, Langedijk Johannes P M, Domingo Mariano, Osterhaus Albert D M E, Ludlow Martin
Abstract excerpt
Long-term persistent measles virus (MeV) infection of the central nervous system (CNS) can result in subacute sclerosing panencephalitis (SSPE), an invariably fatal late neurological complication of measles. Analogous SSPE-like chronic diseases have also been reported in adult dogs, cetaceans, and more recently harbor seals following infection by canine distemper virus (CDV), dolphin morbillivirus (DMV), and...
Topics
- Animals
- Morbillivirus
- Humans
- Morbillivirus Infections
- Genotype
- Phenotype
- Phylogeny
- Subacute Sclerosing Panencephalitis
- Dogs