Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BMP4-Expressing Muscle-Derived Stem Cells Differentiate into Osteogenic Lineage and Improve Bone Healing in Immunocompetent Mice

1 Aug 2002

Abstract excerpt

Recent advances in molecular biology have led the way for novel approaches to improve bone healing. The ideal growth factor, vector, and delivery systems for producing bone in an immune competent animal model, however, have yet to be identified. Using a retrovirus encoding BMP4 and recently isolated muscle-derived stem cells (MDSCs), we demonstrated the following: MDSCs undergo osteogenic differentiation in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Tissue Engineering Materials
Share to Heterotopic Ossification and Related Conditions
Share to Orthopaedic implants and arthroplasty

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12161183
DOI: 10.1006/mthe.2002.0654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BMP4-Expressing Muscle-Derived Stem Cells Differentiate into Osteogenic Lineage and Improve Bone Healing in Immunocompetent MicePMID 12161183Read ↗

Adeno-associated virus-mediated bone morphogenetic protein-4 gene therapy for in vivo bone formation.Semantic proximity Read ↗

BMP-2 generates a functional bone marrow niche by inducing the differentiation of local mesenchymal cells into CAR cellsSemantic proximity Read ↗

Enhancement of Bone Healing Based on <i>Ex Vivo</i> Gene Therapy Using Human Muscle-Derived Cells Expressing Bone Morphogenetic Protein 2Semantic proximity Read ↗

Potential roles of bone morphogenetic proteins (BMPs) in skeletal repair and regenerationSemantic proximity Read ↗

Review: Gene- and Stem Cell–Based Therapeutics for Bone Regeneration and RepairSemantic proximity Read ↗

BMPs and their clinical potentialsSemantic proximity Read ↗

Regional gene therapy with a BMP‐2‐producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodentsSemantic proximity Read ↗

Bone Morphogenetic Protein-2 in Development and Bone HomeostasisSemantic proximity Read ↗

Bone Morphogenetic Protein Gene TherapySemantic proximity Read ↗

Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification.Semantic proximity Read ↗

IN VIVO SOMATIC CELL GENE TRANSFER OF AN ENGINEERED NOGGIN MUTEIN PREVENTS BMP4-INDUCED HETEROTOPIC OSSIFICATIONSemantic proximity Read ↗

Bone morphogenetic proteins: from structure to clinical useSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.