Article
The effect of basic fibroblast growth factor on scarring.
British journal of plastic surgery - 1 Jun 2002
Spyrou G E, Naylor I L
Abstract excerpt
Granulation-tissue myofibroblasts are important in wound contraction, disappearing in normal scars but persisting in hypertrophic scars. While transforming growth factor beta 1 (TGF-beta 1) is implicated in excessive scarring and induces the accumulation of myofibroblasts, the role of basic fibroblast growth factor (FGF-2) on scarring remains unreported. Four linear full-thickness incisions, each 20 mm long, were...
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