Article
Basic Fibroblast Growth Factor Influences Epidermal Homeostasis of Living Skin Equivalents through Affecting Fibroblast Phenotypes and Functions.
Skin pharmacology and physiology - 1 Jan 2018
Yang Lujun, Zhang Dangui, Wu Hongjuan, Xie Sitian, Zhang Mingjun, Zhang Bingna, Tang Shijie
Abstract excerpt
AIMS: To elucidate the possible mechanisms of how basic fibroblast growth factor (bFGF) influences epidermal homeostasis in a living skin equivalent (LSE) model. METHODS: Several wound healing-related growth factors were analyzed at protein and mRNA levels for dermal fibroblasts of induced alpha-smooth muscle actin (α-SMA)-positive or α-SMA-negative phenotypes. During culturing an LSE model by seeding normal...
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