Article
Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis.
Rheumatology (Oxford, England) - 1 Aug 2002
Donn R P, Farhan A, Stevans A, Ramanan A, Ollier W E R, Thomson W
Abstract excerpt
OBJECTIVE: To investigate the involvement of neuroendocrine candidate genes in the aetiopathogenesis of juvenile idiopathic arthritis (JIA). METHODS: Single-nucleotide polymorphisms and intragenic microsatellite markers within five neuroendocrine candidate genes (CRH, CBG, CYP19, ESR1, PRL) were investigated in 463 clinically characterized UK Caucasian JIA patients and a panel of 276 unrelated, healthy UK...
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