Article
Involvement of the hypothalamic-pituitary-adrenal axis in children with oligoarticular-onset idiopathic arthritis.
Annals of the New York Academy of Sciences - 1 Jun 2002
Picco P, Gattorno M, Sormani M P, Vignola S, Buoncompagni A, Battilana N, Pistoia V, Ravazzolo R
Abstract excerpt
Adult patients with rheumatic arthritis and other rheumatic disorders show inappropriate cortisol secretion and peculiar CRH promoter gene polymorphisms. So far, no data are available about this topic in children with juvenile idiopathic arthritis (JIA). We have studied a series of 13 prepubertal patients (10 female, 3 male) affected with oligoarticular JIA (o-JIA) without clinical and biological signs of disease...
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