Article
New developments in frontotemporal dementia and parkinsonism linked to chromosome 17.
Current opinion in neurology - 1 Aug 2002
Rosso Sonia M, van Swieten John C
Abstract excerpt
PURPOSE OF REVIEW: The identification of tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) has revealed invaluable information regarding the role of the tau protein in neurodegenerative disease. Over the past year several new mutations have been identified, and experimental studies have provided further insight into the mechanism of neurodegeneration due to tau mutations...
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