Article
Control of DEMETER DNA demethylase gene transcription in male and female gamete companion cells in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America - 21 Feb 2017
Park Jin-Sup, Frost Jennifer M, Park Kyunghyuk, Ohr Hyonhwa, Park Guen Tae, Kim Seohyun, Eom Hyunjoo, Lee Ilha, Brooks Janie S, Fischer Robert L, Choi Yeonhee
Abstract excerpt
The DEMETER (DME) DNA glycosylase initiates active DNA demethylation via the base-excision repair pathway and is vital for reproduction in Arabidopsis thaliana DME-mediated DNA demethylation is preferentially targeted to small, AT-rich, and nucleosome-depleted euchromatic transposable elements, influencing expression of adjacent genes and leading to imprinting in the endosperm. In the female gametophyte, DME...
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