Article
Anaphylactic transfusion reactions in haptoglobin-deficient patients with IgE and IgG haptoglobin antibodies.
Transfusion - 1 Jun 2002
Shimada Eiko, Tadokoro Kenji, Watanabe Yoshihisa, Ikeda Kazuyo, Niihara Hiromi, Maeda Ikiko, Isa Kazumi, Moriya Susumu, Ashida Takashi, Mitsunaga Shigeki, Nakajima Kazunori, Juji Takeo
Abstract excerpt
BACKGROUND: Patients with haptoglobin deficiency associated with haptoglobin IgG antibodies, who experienced severe nonhemolytic transfusion reactions (NHTRs), have been identified in Japan. Haptoglobin deficiency therefore might be a risk factor for NHTRs. STUDY DESIGN AND METHODS: A total of 4138 cases of voluntarily reported NHTRs in Japan, including 367 cases of immediate-onset anaphylactic NHTRs, were...
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