Article
Detection of JC virus type 1 in peripheral lymphocytes, brain and cerebrospinal fluid from two Korean AIDS patients with progressive multifocal leukoencephalopathy.
Intervirology - 1 Jan 2002
Jeong Byung-Hoon, Jin Jae-Kwang, Choi Eun-Kyoung, Kim Kyung-Hoon, Choi Kang-Won, Oh Myoung-Don, Shin Ki-Chul, Kim Yong-Sun
Abstract excerpt
The human polyomavirus JC virus (JCV) is the etiologic agent of the fatal demyelinating central nervous system disease progressive multifocal leukoencephalopathy (PML), which occurs in 4-7% of AIDS patients. Two Korean AIDS patients with PML were assayed for JCV, and the virus was genotyped by polymerase chain reaction, DNA sequencing and phylogenetic analysis. Using immunohistochemical analysis, we also examined...
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