Article
Prothrombin A19911G and G20210A polymorphisms' role in thrombosis.
British journal of haematology - 1 Aug 2002
Pérez-Ceballos Elena, Corral Javier, Alberca Ignacio, Vayá Amparo, Llamas Pilar, Montes Ramón, González-Conejero Rocio, Vicente Vicente
Abstract excerpt
The prothrombin G20210A polymorphism, which correlates with the plasmatic prothombin levels, is the second genetic risk factor for deep venous thrombosis (DVT), although its prothrombotic role is mild. Recently, the prothrombin A19911G polymorphism, also associated with slight variations of the prothrombin level, has been suggested to modulate the thrombotic risk of the G20210A polymorphism in a preliminary study...
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