Article
Proteomic approaches to central nervous system disorders.
Current opinion in molecular therapeutics - 1 Jun 2002
Rohlff Christian, Southan Christopher
Abstract excerpt
The discovery, design and evaluation of new medicines is critically dependent on the elucidation of protein mechanisms involved in human diseases. Since the proteome of a cell or tissue is not a simple reflection of its transcriptome, direct protein-based analysis is needed. Advances in proteomic technologies are improving the analysis of membrane proteins and signaling complexes with increased speed and...
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