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Article

An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.

The Journal of biological chemistry - 27 Sept 2002

Litterst Claudia M, Pfitzner Edith

Abstract excerpt

Signal transducer and activator of transcription 6 (STAT6) regulates transcriptional activation in response to interleukin-4 (IL-4)-induced tyrosine phosphorylation by direct interaction with coactivators. The CREB-binding protein and the nuclear coactivator 1 (NCoA-1), a member of the p160/steroid receptor coactivator family, bind independently to specific regions of STAT6 and act as coactivators. In this study...

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Source

Identifiers

PMID: 12138096
DOI: 10.1074/jbc.M203556200

Genes

STAT6
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.PMID 12138096Read ↗

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