Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Saccharomyces cerevisiae RNase mitochondrial RNA processing is critical for cell cycle progression at the end of mitosis.

Genetics - 1 Jul 2002

Cai Ti, Aulds Jason, Gill Tina, Cerio Michael, Schmitt Mark E

Abstract excerpt

We have identified a cell cycle delay in Saccharomyces cerevisiae RNase MRP mutants. Mutants delay with large budded cells, dumbbell-shaped nuclei, and extended spindles characteristic of "exit from mitosis" mutants. In accord with this, a RNase MRP mutation can be suppressed by overexpressing the polo-like kinase CDC5 or by deleting the B-type cyclin CLB1, without restoring the MRP-dependent rRNA-processing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Mitosis
Share to Ribonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA, Fungal

Share to RNA, Mitochondrial

Share to RNA Processing, Post-Transcriptional

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 12136008
DOI: 10.1093/genetics/161.3.1029
PMCID: PMC1462176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Saccharomyces cerevisiae RNase mitochondrial RNA processing is critical for cell cycle progression at the end of mitosis.PMID 12136008Read ↗

RNase MRP cleaves the CLB2 mRNA to promote cell cycle progression: novel method of mRNA degradation.Semantic proximity Read ↗

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesisSemantic proximity Read ↗

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesisSemantic proximity Read ↗

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis.Semantic proximity Read ↗

Global identification of new substrates for the yeast endoribonuclease, RNase mitochondrial RNA processing (MRP).Semantic proximity Read ↗

Functions of the mitotic B-type cyclins CLB1, CLB2, and CLB3 at mitotic exit antagonized by the CDC14 phosphatase.Semantic proximity Read ↗

The yeast rRNA biosynthesis factor Ebp2p is also required for efficient nuclear division.Semantic proximity Read ↗

The SIN kinase Sid2 regulates cytoplasmic retention of the S. pombe Cdc14-like phosphatase Clp1.Semantic proximity Read ↗

Mutations in the RNA component of RNase MRP cause a pleiotropic human disease, cartilage-hair hypoplasia.Semantic proximity Read ↗

Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant.Semantic proximity Read ↗

Severely incapacitating mutations in patients with extreme short stature identify RNA-processing endoribonuclease RMRP as an essential cell growth regulator.Semantic proximity Read ↗

Loss of CDC5 function in Saccharomyces cerevisiae leads to defects in Swe1p regulation and Bfa1p/Bub2p-independent cytokinesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.