Article
'Agranular CD4+ CD56+ hematodermic neoplasm' (blastic NK-cell lymphoma) originates from a population of CD56+ precursor cells related to plasmacytoid monocytes.
The American journal of surgical pathology - 1 Jul 2002
Petrella Tony, Comeau Michael R, Maynadié Marc, Couillault Gérard, De Muret Anne, Maliszewski Charles R, Dalac Sophie, Durlach Anne, Galibert Laurent
Abstract excerpt
In 1999, we reported seven cases of an unusual hematologic malignancy with primary cutaneous presentation that appeared as a distinct clinicopathologic entity characterized by medium-sized tumor cells with a peculiar CD3- CD4+ CD56+ CD43+ HLA-DR+ cell surface phenotype. Because the origin of tumor cells was not clear and they exhibited a nonlineage-specific phenotype, we hypothesized that such tumors likely...
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