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Article

Natural killer cell malignancies: clinicopathologic and molecular features.

1 Apr 2002

Abstract excerpt

Malignancies of natural killer (NK) cells have increasingly been recognized as distinct clinicopathological entities. The tumor cells are characterized by an immunophenotype of CD2+, surface CD3-, cytoplasmic CD3epsilon+, and CD56+. The T cell receptor gene is in germline configuration, and a consistent association with Epstein-Barr virus is demonstrable. Pathologically, the tumor cells show variable cytological...

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PMID: 11962758
DOI: 10.14670/hh-17.539

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