Article
Induction and characterization of mutations at the b locus of the medaka, Oryzias latipes.
Zoological science - 1 Apr 2002
Shimada Atsuko, Fukamachi Shoji, Wakamatsu Yuko, Ozato Kenjiro, Shima Akihiro
Abstract excerpt
The b locus is one of the most familiar pigmentation loci in the medaka, but its biochemical function is still unknown. Here we report induction of new mutations at the b locus by radiation and ENU. We also characterized all these mutations and previously isolated spontaneous ones on the phenotypic basis. Unexpectively, all the 18 induced mutations reduced melanin contents in both eyes and skin correlatively,...
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