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Article

Expression of P-glycoprotein in killifish (Fundulus heteroclitus) exposed to environmental xenobiotics.

Aquatic toxicology (Amsterdam, Netherlands) - 24 Sept 2002

Bard Shannon Mala, Bello Susan M, Hahn Mark E, Stegeman John J

Abstract excerpt

P-glycoproteins (P-gp) are transmembrane efflux flippases that prevent the cellular accumulation of moderately hydrophobic compounds and are responsible for certain multidrug resistance phenotypes in tumor cell lines and human patients. We investigated whether P-gps could be involved in a contaminant resistant phenotype observed in a population of fish exposed over generations to high levels of planar halogenated...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12127740
DOI: 10.1016/s0166-445x(01)00256-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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