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Article

The apolipoprotein E2 allele modulates activity and maximal velocity of the sodium-lithium countertransporter.

American journal of hypertension - 1 Jul 2002

Wierzbicki Anthony S, Hardman Timothy C, Cheung Joseph, Lambert-Hammill Michelle, Patel Surinda, Morrish Zoe, Lumb Peter J, Lant Ariel F

Abstract excerpt

BACKGROUND: Alterations in erythrocyte sodium-lithium countertransport (SLC) activity and its maximal velocity (Vmax) are associated with hypertension and hypertriglyceridemia. The presence of apolipoprotein (apo) E variants is associated with hypertriglyceridemia. This study investigated the relationship between apoE phenotype and SLC kinetics. METHODS: Cardiovascular risk factors and SLC kinetics were measured...

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Identifiers

PMID: 12118912
DOI: 10.1016/s0895-7061(02)02927-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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