Article
Macrolide-resistance genes in clinical isolates of Streptococcus pyogenes.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2002
Cascone Carmela, Santagati Maria, Noviello Silvana, Iannelli Francesco, Esposito Silvano, Pozzi Gianni, Stefani Stefania
Abstract excerpt
Macrolide-resistance genes were investigated in 103 macrolide-resistant strains of Streptococcus pyogenes, isolated from children with pharyngotonsillitis. The presence of mef(A), erm(B), and erm(TR) genes was detected by PCR. mef(A) was found in 48 out of 103 (46.6%) strains, whereas erm(B) was detected in 43 isolates (41.7%). All mef(A) strains showed a typical M phenotype (resistance to 14- and 15-membered...
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