Article
Macrolide-resistant genes of Streptococcus pyogenes isolated from the upper respiratory tract by polymerase chain reaction.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Apr 2004
Billal Dewan S, Hotomi Muneki, Yamauchi Kazuma, Fujihara Keiji, Tamura Shinji, Kuki Kiyonori, Sugita Rinya, Endou Miyoko, Mukaigawa Jun, Yamanaka Noboru
Abstract excerpt
The growing number of macrolide-resistant strains of Streptococcus pyogenes is an increasing problem worldwide. This study evaluated 300 clinical isolates obtained from the upper respiratory tract. Minimal inhibitory concentrations (MICs) of erythromycin (EM), azithromycin (AZM), and clindamycin (CLDM), serotypes, and macrolide resistance genes of mefA, ermB, and ermTR were determined. The genetic relationship of...
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