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Article

Pax2.1 is required for the development of thyroid follicles in zebrafish.

Development (Cambridge, England) - 1 Aug 2002

Wendl Thomas, Lun Klaus, Mione Marina, Favor Jack, Brand Michael, Wilson Stephen W, Rohr Klaus B

Abstract excerpt

The thyroid gland is an organ primarily composed of endoderm-derived follicular cells. Although disturbed embryonic development of the thyroid gland leads to congenital hypothyroidism in humans and mammals, the underlying principles of thyroid organogenesis are largely unknown. In this study, we introduce zebrafish as a model to investigate the molecular and genetic mechanisms that control thyroid development....

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Source

Identifiers

PMID: 12117823
DOI: 10.1242/dev.129.15.3751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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