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Article

Promiscuous expression of Epstein‐Barr virus genes in Burkitt's lymphoma from the central African country Malawi

14 May 2002

Abstract excerpt

Primary BL in Malawian children has a very high frequency association, approaching 100%, with the human herpesvirus EBV. A detailed study carried out on viral gene expression in these tumours, using both fresh material and methanol-fixed FNAs, showed, contrary to prediction, that most belong to a variant "class II" latency category, with lytic cycle-related genes also expressed. That is, in addition to EBNA1...

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PMID: 12115495
DOI: 10.1002/ijc.10372

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