Article
Patterns of Epstein-Barr virus latent and replicative gene expression in Epstein-Barr virus B cell lymphoproliferative disorders after organ transplantation.
Transplantation - 15 Aug 1994
Rea D, Fourcade C, Leblond V, Rowe M, Joab I, Edelman L, Bitker M O, Gandjbakhch I, Suberbielle C, Farcet J P
Abstract excerpt
B cell lymphoproliferative disorders arising in organ transplant recipients (B cell posttransplant lymphoproliferative disorders [PTLD]) are generally associated with EBV. In previous reports, B cell PTLD were shown to express the full pattern of EBV latent genes, as in vitro-established lymphoblastoid cell lines. Although viral linear DNA was detected in 40% of lymphoproliferative disorders from...
Topics
- Adult
- Aged
- B-Lymphocytes
- Cell Adhesion Molecules
- Female
- Gene Expression Regulation, Viral
- Herpesvirus 4, Human
- Humans
- Immunophenotyping
- Lymphoproliferative Disorders