Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Depletion of the other genome-mitochondrial DNA depletion syndromes in humans.

Journal of molecular medicine (Berlin, Germany) - 1 Jul 2002

Elpeleg Orly, Mandel Hanna, Saada Ann

Abstract excerpt

We present the current knowledge on the genetic and phenotypic aspects of mitochondrial DNA depletion syndromes. The human mitochondrial DNA encodes 13 of the 82 structural proteins of the mitochondrial electron transport chain. The replication and maintenance of the mtDNA require a large number of nuclear encoded enzymes and balanced nucleotide pools. Mitochondrial nucleotide synthesis is of major importance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Mitochondrial
Share to Gene Deletion
Share to Genome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mitochondrial Diseases

Share to Mutation

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Syndrome

Share to Thymidine Kinase

Source

Identifiers

PMID: 12110944
DOI: 10.1007/s00109-002-0343-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Depletion of the other genome-mitochondrial DNA depletion syndromes in humans.PMID 12110944Read ↗

Inherited mitochondrial diseases of DNA replication.Semantic proximity Read ↗

Defects in mitochondrial DNA replication and human disease.Semantic proximity Read ↗

Inherited mitochondrial DNA depletion.Semantic proximity Read ↗

Syndromes associated with mitochondrial DNA depletion.Semantic proximity Read ↗

Human mitochondrial DNA replication machinery and disease.Semantic proximity Read ↗

Mitochondrial DNA depletion syndromes: review and updates of genetic basis, manifestations, and therapeutic options.Semantic proximity Read ↗

The clinical diagnosis of POLG disease and other mitochondrial DNA depletion disorders.Semantic proximity Read ↗

MtDNA-maintenance defects: syndromes and genes.Semantic proximity Read ↗

Decoding the mitochondria without a code: mechanistic insights into mitochondrial DNA depletion syndromes.Semantic proximity Read ↗

Clinical and molecular features of mitochondrial DNA depletion syndromes.Semantic proximity Read ↗

Disorders of nuclear-mitochondrial intergenomic signaling.Semantic proximity Read ↗

Consequences of compromised mitochondrial genome integrity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.