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Article

Disorders of nuclear-mitochondrial intergenomic signaling.

Gene - 18 Jul 2005

Spinazzola Antonella, Zeviani Massimo

Abstract excerpt

Depletion and multiple deletions of mitochondrial DNA (mtDNA) have been associated with a number of autosomal disorders classified as defects of nuclear-mitochondrial intergenomic signaling. The mendelian forms of progressive external ophthalmoplegia (PEO) are clinically and genetically heterogeneous disorders characterized by the accumulation of multiple deletions of mtDNA in postmitotic patient's tissues. Most...

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Source

Identifiers

PMID: 15921863
DOI: 10.1016/j.gene.2005.03.025

Genes

DGUOK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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